Highly accurate protein structure prediction with AlphaFold

Tony Liang

University of British Columbia

October 3, 2024

Protein and their structure

  • Molecular element that …

  • We know nothing about its structure

How do we know protein structure?

  • X-ray crystallography

  • cryo-electron microscopy

  • NMR spectroscopy

  • These are slow, expensive, limited

Thanks to magical AI

Alphafold

  • Fun story: how this came up initially
  • Easily tell what is protein structure
  • What could be done with this

Future with Alphafold

  • I dont know